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October 1939


Author Affiliations

Attending Dermatologist and Chairman of the Malignancy Board, Los Angeles County Hospital; Chief, Department of Dermatology, Cedars of Lebanon Hospital LOS ANGELES

From the Department of Dermatology, Los Angeles County Hospital.

Arch Derm Syphilol. 1939;40(4):521-540. doi:10.1001/archderm.1939.01490040002001

The treatment of coccidioidal granuloma is of general clinical interest. The endemic character of the infection in certain localities, together with its frequently serious clinicopathologic manifestations and effects, constitutes a challenging demand for effective therapeutic efforts. That such efforts have heretofore proved only partially successful may be readily gleaned from a survey of the available literature dealing with the subject. This will reveal a large variety of therapeutic agents employed in the management of the disease and a correspondingly large variety of contradictory claims of success and failure resulting from their exhibition by the different clinicians.

REVIEW OF THE LITERATURE  Guy and Jacob1 obtained successful therapeutic results in a case of tuberculosis and coccidioidal granuloma by roentgen irradiation of the lesions and intravenous injections of a 1 per cent solution of antimony and potassium tartrate. The injections were administered on alternate days in increasing doses, commencing with 1 cc.

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