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October 1939


Arch Derm Syphilol. 1939;40(4):603. doi:10.1001/archderm.1939.01490040084010

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To the Editor:—  Dr. Walter F. Lever's report on the availability of absorbed iodine on the iodide of a bile salt as a source of free iodine (Iodocholeate: A New Fungicidal Preparation, Arch. Dermat. & Syph.40:19 [July] 1939) reaffirms the advantages of this form of iodine over free iodine solutions in the treatment of fungous infections. Iodine-releasing mixtures or compounds are of two kinds: Either (1) the available iodine is absorbed on a carrier or (2) it is part of an unstable iodide that slowly disintegrates, releasing elemental iodine. Ideally, the mixture of choice is one in which the percentage content of iodine is high, all the contained iodine may be released in elemental form and even the residue may be of fungistatic or fungicidal value.The late Walter Highman and I used and reported on such a compound (The Use of Tetraiodomethenamine in Flexible Collodion in the

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