This communication is a summary of certain data obtained from the study of 34 patients with pemphigus. All the patients were admitted to the outpatient department or to the wards of the Massachusetts General Hospital between 1935 and 1939, inclusive. The ages varied from 4 to 76. There were 19 men and 15 women. The nomenclature of the types of pemphigus which we have used and will retain in this discussion varies somewhat from that in contemporary textbooks. The pemphigus in our patients has been classified simply as acute or chronic.
The acute form may be distinguished clinically by the early development of lesions in the mouth, a rapid, fulminating course, racial susceptibility (8 of the 10 patients with acute pemphigus in our series were Jews) and a high incidence in the fourth and fifth decades of life. Further, this form may be distinguished chemically by certain abnormalities in the
TALBOTT JH, COOMBS FS. PEMPHIGUS: EXPERIMENTAL STUDIES ON THIRTY-FOUR PATIENTS. Arch Derm Syphilol. 1940;41(2):359–369. doi:10.1001/archderm.1940.01490080168009
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