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Article
March 1940

DISSEMINATED LUPUS ERYTHEMATOSUS TREATED BY SULFANILAMIDEREPORT OF FOUR CASES

Arch Derm Syphilol. 1940;41(3):534-544. doi:10.1001/archderm.1940.01490090086011
Abstract

The syndrome known as disseminated lupus erythematosus has received increasing recognition in the recent literature. The cause of the disease remains unknown, and relatively little has been written concerning the treatment. It is the purpose of this paper to report some experiences with the use of sulfanilamide in the treatment of disseminated lupus erythematosus.

There is no known effective therapy for the disease. Most cases reach a fatal termination in from several weeks or months to several years. Stokes1 stated that he had never seen a patient with disseminate erythematous lupus survive for more than five years. It is difficult to prognosticate for a given case, but in general one can say that the prognosis is poorest in the exanthematous types and best in the less fulminating disseminate discoid variety. Most cases within the latter group are not fatal. Belote's2 recent classification of lupus erythematosus, while based on

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