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Article
April 1940

NEW YORK ACADEMY OF MEDICINE, SECTION OF DERMATOLOGY AND SYPHILOLOGY

Arch Derm Syphilol. 1940;41(4):761-771. doi:10.1001/archderm.1940.01490100125021

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Abstract

Arsenical Dermatitis with Pigmentation and Alopecia. Presented by Dr. Jesse A. Tolmach and Dr. A. Franks (by invitation).  M. H., a woman aged 25, is presented from the Skin and Cancer Unit of the New York Post-Graduate Medical School and Hospital. In September 1938 the patient was found to have a positive Wassermann reaction of the blood during the course of an examination by a private physician for a vesicular eruption on the hands. Intravenous injections of arsphenamine were begun at weekly intervals. After the second injection, a red raised lesion about the size of a quarter appeared on the flexor surface of the right wrist. After the fifth or sixth injection a circumoral and supraorbital erythematous eruption developed, and the eyebrows began to fall out. After six doses of neoarsphenamine and six doses of a bismuth compound, she was given a rest period of one week, after which another

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