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April 1940


Arch Derm Syphilol. 1940;41(4):806-816. doi:10.1001/archderm.1940.01490100170026

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Incipient Granuloma Inguinale.  Presented by Dr. Louis Chargin.W. W., a Negro laborer aged 35, was admitted to the Central Social Hygiene Clinic of the Department of Health on Sept. 22, 1939, presenting a lesion on the shaft of the penis of nine weeks' duration.On the dorsum of the lower third of the shaft is a well circumscribed ulceration the size of a dime. The base is a dirty gray, and the borders are raised and somewhat undermined. The lesion shows only slight induration. The inguinal lymph nodes are not enlarged. Dark field examination for spirochetes gave negative results. The Ito test (Lederle Ducrey bacillus vaccine) and the Frei test gave negative results. Smears for Ducrey bacilli were negative on repeated examination. In view of the fact that the lesion resembled chancroid, sulfanilamide was administered for two weeks, without appreciable effect. At this time examination of smears revealed the

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