The term malignant in respect to pemphigus vulgaris is herein used to describe those types with which there is apparently going to be a fatal termination, as against the benign types from which recovery occurs. I am not in sympathy with the thought that when a patient with clinically clear pemphigus vulgaris recovers that patient did not really have pemphigus vulgaris. There are undoubted cases of clinically well marked pemphigus vulgaris in which a fatal prognosis has been given but, surprisingly, complete recovery occurs and there are no subsequent remissions.
So far as I have been able to ascertain, the only recorded instance in the American literature of familial malignant pemphigus vulgaris is that by Feldman,1 who three years ago reported the disease in 2 brothers, both of whom died, 1 with pemphigus vulgaris of many months' duration and the other with pemphigus vulgaris of much shorter duration. In
GREENBAUM SS. CASES OF FAMILIAL AND OF CONJUGAL PEMPHIGUS VULGARISUSE OF TRANSFUSIONS OF BLOOD FROM CURED PATIENTS. Arch Derm Syphilol. 1940;41(6):1073–1075. doi:10.1001/archderm.1940.01490120075010
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