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T.B., a man aged 44, was first seen in June 1938. Six years previously he had had an initial lesion, for which he had received some irregular treatment with an arsenical and a bismuth compound.
The Wassermann reaction of the blood was strongly positive. Physical examination gave essentially negative results. He was definitely psychopathic and homosexual in his inclinations, and treatment by several psychiatrists had failed to produce any improvement. Examination of his spinal fluid showed a strongly positive Wassermann reaction and a gold curve suggestive of early dementia paralytica. Cytologic and chemical examinations were not made.
Over a period of five months he was given tryparsamide, arsphenamine, a bismuth compound and intravenous injections of colloidal mild mercurous chloride. His general health improved, and the Wassermann reaction was reduced to 1 plus. No amount of persuasion would change his homosexual habits. He lived with a woman with whom he indulged
Combes FC. SUPERINFECTION IN SYPHILISReport of a Possible Case. Arch Derm Syphilol. 1940;41(6):1108–1109. doi:10.1001/archderm.1940.01490120110015
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