The lipoidoses, as one of us (E. U.) explained elsewhere,1 are now classified in two large groups, namely, the general and the local lipoidoses. This division is based on demonstration of the fact that in the former there is a general, primary disturbance of fat metabolism, whereas in the latter there is a local disease of the tissue with secondary deposition of fat.
The general lipoidoses represent a process of fatty infiltration; their further classification is based on clinical type, the nature of the lipoid (cholesterol ester, free cholesterol, phosphatide, lecithin or kerasin), the intracellular or extracellular presence of the lipoid and the histologic features. The table presents a summary of these items.
The xanthelasmatoses (this term is preferable to xanthoma, because a blastomatous character is demonstrable only in extremely rare instances) can at present be classified only from a clinical point of view, because histologically and chemically no
URBACH E, HILL WR. A PROPOSED CLASSIFICATION OF CUTANEOUS LIPOIDOSESWITH DESCRIPTION OF A NEW LOCAL LIPOID DERMATOSIS: IMBIBITIO LIPOIDICA COLLAGENI DEGENERATI CUTIS. Arch Derm Syphilol. 1940;42(1):68–85. doi:10.1001/archderm.1940.01490130072010
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