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September 1940


Author Affiliations


From the Laboratories and Service of Dr. Isadore Rosen, Mount Sinai Hospital, and from the Skin and Cancer Unit of the New York Post-Graduate Medical School and Hospital.

Arch Derm Syphilol. 1940;42(3):426-437. doi:10.1001/archderm.1940.01490150030005

If living fungi can be disseminated hematogenously from a primary focus to other areas of the skin, they can give rise either to new areas of mycotic infections or to dermatophytids. It has been suggested that these secondary lesions would be more common were it not for the fact that contact of the fungi with the circulating blood reduces their virulence1 and even causes their destruction.2

Per and Braude,3 as well as Jessner and Hoffman,1 have apparently demonstrated fungicidal antibodies in patients with fungous infections. Furthermore, Ayres and Anderson2 maintained that only patients with trichophytids have such humoral fungicidal substances. Based on such a premise, Traub and Tolmach4 used "convalescent serum" from patients with dermatophytids in the treatment of fungous infections. Lewis and Hopper5 were unable to substantiate the findings of Ayres and Anderson.2

These rather isolated but more or less related