One is hesitant to add to the long list of therapeutic agents for use in the treatment of acne, but the disease is so common and the therapeutic results are so mediocre that any help may be welcome. The oral administration of nicotinic acid was suggested by a co-worker's statement that seborrhea appeared to be favorably influenced by this drug. It was then given to 46 university students who had had no previous treatment for acne or no treatment for at least three months preceding their trial of this drug. The nicotinic acid was administered twice daily in the form of 50 mg. tablets taken after the morning and evening meals. No other treatment was used, and the students were given no advice as to diet or hygiene.
The only unpleasant reaction observed in this group of patients was transitory redness, burning or itching in the flush areas of the
Lynch FW. NICOTINIC ACID IN THE TREATMENT OF ACNE VULGARIS. Arch Derm Syphilol. 1940;42(3):481–482. doi:10.1001/archderm.1940.01490150085017
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