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Symposium on Syphilis
Acute Hemorrhagic Encephalitis Due to Neoarsphenamine, with Recovery. Presented by Dr. Nathan Sobel.
M. R., a man aged 28, a clerk, is presented for Dr. Nathan Pensky, to whom he was referred on Oct. 1, 1939, because of a 4 plus Wassermann reaction. He stated that he had never had a venereal disease but gave a history of a quiescent duodenal ulcer. Physical examination at that time showed that the right pupil was slightly unequal and reacted sluggishly to light. Otherwise, the central nervous system and the heart were normal. The Wassermann reaction of the blood was 4 plus on three successive examinations. At that time the patient refused to allow a lumbar puncture.Therapy was instituted with bismuth in oil in doses of 2 cc. once a week for five weeks. This was well tolerated. In the sixth week 0.3 Gm. of neoarsphenamine was administered. One
Abramowitz EW, Robinson LB. NEW YORK ACADEMY OF MEDICINE, SECTION OF DERMATOLOGY AND SYPHILIS. Arch Derm Syphilol. 1940;42(4):665–673. doi:10.1001/archderm.1940.01490160125021
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