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November 1940


Arch Derm Syphilol. 1940;42(5):933-936. doi:10.1001/archderm.1940.01490170183017

The infectious (virus) nature of many herpetiform eruptions has been established by the production in animals and in human beings of comparable reactions in skin or mucous membrane from inoculation with material from spontaneously evoked lesions. Concerning herpes febralis and herpes progenitalis, similar studies have led to the conclusion that their respective viruses are immunologically distinct, a distinction corroborated by the epidemiologic features of both.1

Long before a virus became suspected, nineteenth century clinicians of wide experience were sufficiently impressed with the persistent history of venereal disease in patients presenting genital herpes to surmise a venereal origin for the latter. Yet no single, unequivocal case history is recorded that establishes this clinical picture as a venereal contagion in its own right. For this reason the following short reports of 2 cases are recorded. The absolute reliability of the pertinent facts cogently argues acceptance of the theory of a venereal

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