A case of hereditary edema of the legs with other congenital anomalies recently came under my observation. Hereditary edema of the legs being rare, its combination with other congenital anomalies warrants reporting this case as one of unusual interest.
REPORT OF A CASE
L. L., a white woman aged 28, was first seen at the Northwestern University Medical School on April 15, 1939. She stated that her limbs had been enlarged since infancy and that her mother and an aunt had the same condition. The enlargement appeared soon after her birth and gradually progressed during her growth and development. She had experienced no discomfort until about one and one-half years before her appearance at the clinic, when painful swelling of both feet developed, more evident during the afternoon and evening. Rest at night, however, did not materially reduce the swelling or relieve the pain. Properly fitted shoes were prescribed and
ROSENBERG WA. HEREDITARY EDEMA OF THE LEGS (MILROY'S DISEASE): ASSOCIATED WITH OTHER CONGENITAL ANOMALIES. Arch Derm Syphilol. 1940;42(6):1113–1121. doi:https://doi.org/10.1001/archderm.1940.01490180122010
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