Leukoderma acquisitum centrifugum is a relatively rare condition, but several articles on this subject have appeared since Sutton1 reported his 2 cases in 1916. The literature and the various theories proposed to explain the mechanism of the production of these lesions were adequately reviewed by Feldman and Lashinsky2 in 1936, but I was unable to find any report of what effect, if any, on the surrounding leukodermic area would follow destruction of the central nevus. If, as some authors assume, the nevus drains pigment from the surrounding area, theoretically destruction of the nevus might permit the leukodermic area to regain its normal supply of pigment. An opportunity to study this question was afforded me by a patient with typical lesions of leukoderma acquisitum centrifugum who came to the clinic for removal of the pigmented nevi.
REPORT OF CASE
F. S., a white girl aged 13, was first seen
NILES HD. LEUKODERMA ACQUISITUM CENTRIFUGUM: REPORT OF A CASE IN WHICH THE CENTRAL NEVI WERE DESTROYED AND THE LEUKODERMIC HALOES THEN TREATED WITH ULTRAVIOLET RADIATION IN AN ATTEMPT TO RESTORE THE PIGMENT. Arch Derm Syphilol. 1941;43(2):357–360. doi:10.1001/archderm.1941.01490200139012
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: