Adequate understanding of the significance of the endocrine glands involves the realization that no one of the hormones is entirely indispensable for the maintenance of life in the human body. Although such a statement seems to contradict the well known importance of such glands as the adrenals and the pancreas, special conditions can be arranged so that life continues for some time without secretions from these structures. There is no desire to minimize the importance of glands of internal secretion or of hormones, but their true function must be stated in terms of catalyzing or facilitating chemical processes which are going on without the hormone, even though sometimes at very low speed. Life will go on without the normal catalysis of any one of these hormone-facilitated processes, although it may be at such an altered speed that the condition must be classed as a disease. In a few cases this
SEVRINGHAUS EL. ENDOCRINE GLANDS AND THEIR RELATION TO DERMATOLOGY. Arch Derm Syphilol. 1941;43(5):763–774. doi:10.1001/archderm.1941.01490230003001
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