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May 1941


Author Affiliations


From the Brooklyn Cancer Institute.

Arch Derm Syphilol. 1941;43(5):809-812. doi:10.1001/archderm.1941.01490230049005

In 1935 Lumière, Gate, Michel and Dugois1 described a case of neoplasm of the face of the pseudoactinomycotic type. The case gave the authors a great deal of difficulty in diagnosis. Histologic examination of the lesion showed no malignancy. All other laboratory tests failed to identify the lesion. Because of the suppurative character of the lesion and the edematous infiltration of the chin a clinical diagnosis of actinomycosis was made, and the patient was treated accordingly. The treatment was of no avail, and the patient died later from bronchopneumonia. Histologic study of postmortem sections of all the lesions resulted in a diagnosis of epithelioma.

A similar patient with pseudoactinomycotic carcinoma was admitted to the Brooklyn Cancer Institute in 1938. A comparative study of the clinical and histologic observations and photographs of the two lesions proved that they are identical. This case is the only one of its kind encountered