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May 1941


Author Affiliations

San Francisco

From the Division of Dermatology and Syphilology, Department of Medicine, Stanford University School of Medicine, service of Dr. Harry E. Alderson.

Arch Derm Syphilol. 1941;43(5):846-847. doi:10.1001/archderm.1941.01490230086013

Little study has been made of the effect of sulfanilamide and its derivatives on infections due to the bacillus of swine erysipelas (erysipeloid). The only report that has come to our attention is that of Schoch and Shelmire,1 in 1940, who stated the belief that sulfanilamide therapy was of some value in the treatment of erysipeloid on the basis of the success attained in 3 of 4 patients treated. In the fourth patient, as the infection continued to extend after six days of chemotherapy, the drug was regarded as being ineffective. Because of the variable course of erysipeloid, as Klauder2 has emphasized, the evaluation of treatment is somewhat difficult. However, because of the rapid response to treatment with sulfathiazole (2-sulfanilamidothiazole) and the relative rarity of erysipeloid, we are prompted to report the results obtained with this compound used to the exclusion of other measures in the treatment of