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Multiple Epitheliomas Due to Arsenic. Presented by Dr. John D. Rodgers (by invitation).
A man aged 55, a bookkeeper, complained of an eruption on the forearms, the dorsal surfaces of the hands, the back and the legs. A lesion first appeared on the left shoulder about four years ago and spread until it is now 5 by 6 cm. in size. On the right knee is a nodular area 4 by 2.5 cm. in size. On both legs are well defined smaller firm nodular lesions surrounded by a raised erythematous brown border. There are many small ulcerated areas on the hands. The patient gave a history of medication with solution of potassium arsenite U. S. P. many years ago.The histologic examination showed a squamous cell epithelioma of the shoulder, grade 3, and a basal cell epithelioma of the scalp. The Wassermann reaction of the blood was negative.The treatment