The discovery of the potentialities of sulfanilamide and its derivatives has been referred to as "the greatest therapeutic achievement in modern medicine." Not since Ehrlich's epoch-making discovery of arsphenamine has a remedy of such specificity and utility been offered to the world. The literature on the clinical and experimental aspects of this group of drugs is enormous. However, several years must elapse before definite indications, proper dosage and methods of administration are determined.
It is our purpose to state our opinion concerning the value and limitations of sulfanilamide and allied compounds in dermatologic practice, including in addition that of dermatologists from all sections of the United States and of many foreign correspondents.1 Since the literature was reviewed recently by Hughes,2 we have eliminated many references, citing only a few of those not mentioned by this author.
The history of the development of these drugs and the complete study
COMBES FC, CAÑIZARES O. SULFANILAMIDE AND ALLIED COMPOUNDS: THEIR VALUE AND LIMITATIONS IN DERMATOLOGY. Arch Derm Syphilol. 1941;44(2):236–247. doi:10.1001/archderm.1941.01500020091009
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