Four years ago I treated a woman with recurrent lymphangitis with sulfanilamide.1 It is fitting that further observations of this case should be recorded, particularly since it was the first one of chronic lymphangitis of the upper lip reported in which sulfanilamide therapy was used.
The lip is now entirely normal in size, having become progressively smaller and softer during the past two years. No exacerbations such as were formerly experienced have been noted on exposure to sunlight, on smoking of cigarets, during rainy weather or on exposure to the fumes of paint. The ingestion of alcoholic drinks continues to cause a mild transient enlargement.
A slight swelling of the lip has taken place approximately eight times. Each attack has been accompanied by a cold, and each time the swelling (an enlargement estimated to be approximately one tenth of the normal size of the lip) has been promptly controlled
Mercer SR. RECURRENT LYMPHANGITIS TREATED WITH SULFANILAMIDE: Further Observations on a Case. Arch Derm Syphilol. 1941;44(3):465. doi:10.1001/archderm.1941.01500030147017
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