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F. M., a woman aged 40, was first seen by me on April 24, 1941, when she applied for treatment of dermatitis which had occurred periodically on the left side of the face during the past year. The eruption consisted of erythema and fine papules on the ramus of the left jaw and on the eyelids.
After the suggestion was made that the condition might be due to the highly colored nail polish she wore, she recalled an incident which had occurred prior to the onset of the dermatitis. While at work she spilled a bottle of ink eradicator and noted at the time that the odor was the same as that of nail polish. After mopping up the fluid with a cloth, she noted itching of the face.
Patch tests were made with the aforementioned fluid and with face powder, rouge, lipstick and nail polish. Erythema and papules appeared