The concept of membranous stomatitis includes a host of conditions characterized by the formation of a membranous deposit in one or more areas in the oral cavity. When a definite etiologic agent can be identified (Bacillus diphtheriae, Vincent's organisms or Spirochaeta pallida) or when the lesions can be classified within a circumscribed category (pemphigus or erythema multiforme exsudativum), the specific term membranous stomatitis may be applied in a general way. There are, however, numerous other ill defined membranous lesions in the mouth about which present knowledge is scanty in practically all particulars, especially in their histologic aspects. It is with a view to the clarification of this heterogeneous group of conditions that the present report is written.
Pathologists differentiate a pseudo membranous inflammation (membrane formed chiefly of exuded inflammatory fibrin) from a true membranous deposit (membrane consisting only of coagulated or necrotic epithelium). In practically all examples of stomatitis the
BERESTON ES, KEIL H. MEMBRANOUS STOMATITIS ASSOCIATED WITH DEBILITATION AND WITH UREMIA. Arch Derm Syphilol. 1941;44(4):562–570. doi:10.1001/archderm.1941.01500040017002
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