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November 1941


Arch Derm Syphilol. 1941;44(5):931-942. doi:10.1001/archderm.1941.01500050161025

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Scleroderma (Localized Type). Presented by Dr. Morris Markowitz and Dr. Sigmund S. Greenbaum.  K. B., a white man aged 62, presents moderately thickened atrophic macules and plaques distributed on the neck and chest, in the lumbosacral region and on the right lower extremity. There are no subjective symptoms. The eruption first appeared about a year and a half ago, coincident with repeated attacks of colitis with diarrhea. The Wassermann reaction of the blood was negative, and the blood count was normal. Routine chemical examination of the blood showed no abnormalities except a high cholesterol content, 395 mg. per hundred cubic centimeters. The patient was treated for pulmonary tuberculosis some years ago, with apparent complete arrest of the disease. Moderate improvement of the cutaneous lesions has been noted during the past six weeks following treatment with ammonium chloride, 0.5 Gm. given by mouth twice a day.

DISCUSSION  Dr. Fred D. Weidman

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