The treatment of the discoid type of lupus erythematosus with gold salts has not been entirely satisfactory. For example, Rutledge1 in 1931 in reporting 56 cases stated that in 30 the condition was improved and in 18 arrested. Wright2 in 1936 reported a series of 76 patients treated by this method, of whom 37 per cent were regarded as cured, 34 per cent as almost cured or greatly improved and 17 per cent as moderately or slightly improved; 12 per cent failed to respond favorably. He also stated that 17 per cent of the 76 patients suffered one or more relapses after being partially or entirely free from lesions and that 24 per cent of the patients suffered a reaction of one type or another from the gold treatment. In the same year Alden and Jones3 reported that in 33 per cent of their cases the disease
WEISS RS, CONRAD AH, CONRAD AH, PFAFF RO. XCVI. TREATMENT OF LUPUS ERYTHEMATOSUS WITH BISMARSEN. Arch Derm Syphilol. 1941;44(6):1009–1030. doi:10.1001/archderm.1941.01500060028003
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