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December 1941


Author Affiliations


From the Department of Dermatology and Syphilology, University of Texas Faculty of Medicine.

Arch Derm Syphilol. 1941;44(6):1051-1054. doi:10.1001/archderm.1941.01500060070005

The case of Fox-Fordyce disease to be reported conforms in general with most of the cases described since the original report, in 1902.1 The eruption in its appearance and course was typical; resistance to treatment was characteristic, and the histologic picture agreed in the main with that in other cases. Additional observations are recorded which were considered of enough interest to warrant this report.

REPORT OF CASE  C. S., a Negress aged 37, unmarried, was under treatment for latent syphilis for two years prior to the present complaint. During this time she received twenty-two injections of arsenicals, including both neoarsphenamine and mapharsen (total dose 1.32 Gm.), and forty-eight injections of a bismuth compound.Points of interest in her past history are one full term pregnancy fifteen years previous to consultation and painful nodules in the breast two years previously. There were no menstrual irregularities until the last two menses,