Since a review of the literature on juvenile dementia paralytica from January 1936 on reveals little or no reference to the use of artificial fever therapy and no specific reference to results, we feel that publication of our small series would be of interest to the members of the medical profession.
In Menninger's comprehensive monograph on juvenile dementia paralytica1 no reference was made to the use of fever therapy except that of malaria. This author considered the outlook in this disease as unfavorable under any type of treatment but stated that malaria may produce a more persistent and more complete remission than chemotherapy. He pointed out that chemotherapy should always follow the course of malaria. Bennett, Nielsen, Fechner and Cash2 indicated in 1939 that they had tried it in 1 case. There have been many uses of fever therapy in its various forms, in particular, malaria.3 It
NIELSEN JC, MARX JR, DICKEL HA. ARTIFICIAL FEVER THERAPY IN JUVENILE NEUROSYPHILIS. Arch Derm Syphilol. 1942;45(4):688–693. doi:10.1001/archderm.1942.01500100049005
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