Just as there is considerable difference of opinion relative to the criteria for diagnosis of benign neoplasia of various glandular structures throughout the body, so some confusion exists in the evaluation of benign neoplastic growths of the sebaceous glands of the skin. A benign neoplasm of a glandular structure is called an adenoma. In a discussion of this designation, Ewing1 stated:
When one considers the great variety of conditions, in which an adenomatous morphology is presented, and analyzes their physiological and clinical significance, the conclusion must be reached that adenoma is rarely a distinct morphological entity, but is rather to be regarded as a series of structures which tissues assume in response to various forms of irritation, functional activity, and overgrowth.
Beck2 emphasized the differences of opinion relative to classification of abnormal growths originating in the sebaceous glands. Gans3 stated:
It seems, therefore, worthy of recommendation that
WOOLHANDLER HW, BECKER SW. ADENOMA OF SEBACEOUS GLANDS (ADENOMA SEBACEUM)WITH CONSIDERATION OF KERATOTIC ADENOMA SEBACEUM AND TRUE ADENOMA OF SEBACEOUS GLANDS. Arch Derm Syphilol. 1942;45(4):734–756. doi:10.1001/archderm.1942.01500100095009
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