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The use of sulfur (in its various feebly bacteriostatic forms) in the local treatment of pustular acne has never seemed rational. I have not been surprised at the poor results obtained.
Recently I have been adding 5 per cent sulfathiazole (2-[paraaminobenzenesulfonamido]-thiazole) to the ordinary sulfur shake lotion and have found that the number of pustules is usually conspicuously reduced after the patient has used the preparation for three weeks. I feel that the sulfathiazole portion of the lotion is responsible for the reduction of pustules, while the sulfur portion has the usual keratolytic effects.
Medical Arts Building.