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Article
April 1942

A RATIONAL APPLICATION FOR PUSTULAR ACNE: SULFUR LOTION WITH SULFATHIAZOLE

Arch Derm Syphilol. 1942;45(4):762. doi:10.1001/archderm.1942.01500100123012

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Abstract

The use of sulfur (in its various feebly bacteriostatic forms) in the local treatment of pustular acne has never seemed rational. I have not been surprised at the poor results obtained.

Recently I have been adding 5 per cent sulfathiazole (2-[paraaminobenzenesulfonamido]-thiazole) to the ordinary sulfur shake lotion and have found that the number of pustules is usually conspicuously reduced after the patient has used the preparation for three weeks. I feel that the sulfathiazole portion of the lotion is responsible for the reduction of pustules, while the sulfur portion has the usual keratolytic effects.

Medical Arts Building.

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