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April 1942


Arch Derm Syphilol. 1942;45(4):787-805. doi:10.1001/archderm.1942.01500100148017

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Acquired Multiple Pigmented Nevi. Presented by Dr. Francis E. Senear and Dr. Theodore Cornbleet.  B. C., a white woman aged 24, presents multiple grouped dark brown pinhead-sized to slightly larger macules on the torso, extending from the buttocks to the breasts. For the past year these macules have appeared in increasing numbers, and none have disappeared, so far as the patient knows.Histologic examination of a biopsy specimen from a lesion on the buttock showed a considerable amount of melanin pigment, the pigment granules being densely packed in the basal layer of the epidermis, in the follicle and in the cells around the follicle.

DISCUSSION  Dr. S. W. Becker: The patient's flat brown macules under the microscope show localized collections of so-called nevus cells which are still, at least in this one section, all attached to the epithelium. This is the same condition that obtained in the patient whose case

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