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Pyoderma Gangraenosum. Presented by Dr. Maurice J. Costello.
I. N., an unmarried Negress aged 23, is presented from Bellevue Hospital with an ulcer on the right leg. About ten years ago, following a bruise incurred against the edge of a table, a sore appeared, which soon became much larger. After a year of local therapy with salves and powders, together with iron internally, the ulcer healed; but it recurred after about nine months and has never healed since.The patient has received extensive antisyphilitic treatment for the past four years but pleads ignorance as to how she acquired the disease. Her past history is essentially irrelevant.Examination shows a single oval ulcer, about 4 by 2 inches (10 by 5 cm.), located on the inner aspect of the lower third of the right leg. It has a clean, granulating base and is surrounded by thick, indurated, gray scar tissue.The