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June 1942


Arch Derm Syphilol. 1942;45(6):1210-1218. doi:10.1001/archderm.1942.01500120178025

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Keratosis Palmaris et Plantaris (Congenital). Presented by Dr. Samuel Ayres Jr.  S. B., a white boy aged 11 years, presents hyperkeratosis of the palms and soles, consisting of thickened yellowish areas, with a rather sharp line of demarcation along the sides of the feet and hands. These changes first appeared when the patient was about 6 weeks old. The father, one of eleven children, is the only member of the family known to suffer from a similar condition.

DISCUSSION  Dr. L. F. X. Wilhelm: I agree with the diagnosis. I have nothing to offer as to therapeutic possibilities.Dr. Samuel Ayres Jr.: I presented this case for the purpose of hearing discussion as to whether a patient with this disease might be benefited by vitamin A therapy in view of the changes reported in some cases of ichthyosis and in Darier's disease.

Necrobiosis Lipoidica Diabeticorum. Presented by Dr. Samuel Ayres 

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