Because we have received numerous inquiries since the publication of our preliminary report1 on intensive arsenotherapy of early syphilis, we thought it advisable to outline briefly the added experience which we have had with the method.
To date we have treated over 350 patients. Of these, 208 were treated by the ten day syringe method, the technic consisting of giving 120 mg. of mapharsen daily for ten consecutive days (a total of 1,200 mg.) by rapid syringe injection. The remaining 142 patients have been treated with a revised system, consisting of giving smaller individual doses over a longer period of time. It approaches somewhat the original plan 1 by which we treated our first 8 patients.
In 1 case it was severe and resulted in death; in the second case it was moderately severe and resulted in recovery, and in the third case the encephalitis was questionable and also