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July 1942


Arch Derm Syphilol. 1942;46(1):139-140. doi:10.1001/archderm.1942.01500130142015

The paucity of reports on the successful treatment of virus diseases with sulfanilamide and its derivatives justifies the recording of clinical impressions gained from their employment in cases of this group of diseases.

Schnitker1 stated that lymphogranuloma venereum was the only virus infection which responded to these drugs.

In a recent article Sommerville2 wrote that molluscum contagiosum, a virus disease limited strictly to the skin, was cured by the oral use of sulfapyridine (2-[paraaminobenzenesulfonamido]-pyridine). He reported 8 cases, with clinical cures in 6. Two patients experienced early toxic reactions, discontinued treatment and lapsed from observation. Of the 6 cured patients, 4 who took the sulfanilamide compound regularly were cured at varying periods, ranging from two to eight weeks. Three to four months elapsed, however, before final cure was effected in the 2 persons who used the drug at irregular intervals. The effective daily dose of the drug varied

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