A review of the literature in the English language has revealed no report of a case of vulvovaginocervical eruption due to the therapeutic administration of gold sodium thiosulfate. This may be because no such lesions have previously occurred or because if they are present in a patient showing toxic manifestations they have been either overlooked or, if discovered, not reported. Although gold sodium thiosulfate undoubtedly causes a vulvovaginocervical eruption rarely and perhaps never without causing a simultaneous generalized cutaneous eruption, we feel that the medical literature should contain a record of its occurrence. Perhaps knowledge that such lesions may exist will lead to the discovery and reports of additional cases.
REPORT OF A CASE
B. K., a white married woman aged 37, with two children, had her menarche at the age of 13, and her menstrual cycle was regular. She was first admitted to the arthritis clinic on April 11,
BARROWS DN, STONE ETR. VULVOVAGINOCERVICAL ERUPTION DUE TO THERAPY WITH GOLD SODIUM THIOSULFATE. Arch Derm Syphilol. 1942;46(2):250–253. doi:10.1001/archderm.1942.01500140066010
Customize your JAMA Network experience by selecting one or more topics from the list below.