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Article
September 1942

XCIV. A NEW APPROACH TO THE PROBLEM OF DISSEMINATED NEURODERMATITIS

Arch Derm Syphilol. 1942;46(3):337-347. doi:10.1001/archderm.1942.01500150003001
Abstract

Chronic disseminated neurodermatitis, or atopic dermatitis, as it is called in the more recent literature, has long been recognized as a distinct, well defined clinical entity. The older writers, Vidal,1 Brocq and Jacquet,2 Besnier,3 Czerny4 and others, have given accurate descriptions of its symptoms and clinical course and have propounded theories as to its cause. Some of these older writers tended to include the localized types of lichenification with disseminated dermatitis, but this confusion has been clarified by several of the modern observers, such as Sulzberger5 and Brunsting,6 who have shown that lichen simplex chronicus or localized neurodermatitis and chronic disseminated neurodermatitis are not identical.

Disseminated neurodermatitis begins usually in infancy as an acute or chronic dermatitis distributed characteristically over the cheeks and extensor surfaces of the arms and legs or in some instances widely generalized. The infantile form undergoes exacerbations and remissions as

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