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Article
September 1942

CUTANEOUS SENSITIVITY TO MERTHIOLATE AND OTHER MERCURIAL COMPOUNDS

Author Affiliations

Captain, Medical Corps, United States Army BALTIMORE

From the Department of Dermatology, University of Maryland School of Medicine.

Arch Derm Syphilol. 1942;46(3):425-430. doi:10.1001/archderm.1942.01500150091011
Abstract

Some investigators claim that if a patient's skin is sensitive to one of the mercurials he may be sensitive to any compound containing mercury. We have investigated 5 patients with dermatitis due to merthiolate and found that 4 were sensitive to merthiolate and not to any other organic or inorganic mercury compounds with which they were tested.

Gross1 reported on a patient who was sensitive to mercurophen (sodium hydroxymercury orthonitrophenolate). The patient was sensitive also to tincture of metaphen, 2 per cent yellow mercuric oxide ointment, 1: 10,000 solution of mercury bichloride and 3 per cent mercurous chloride ointment but reacted negatively to patch tests with tincture of merthiolate and mercurochrome. Butterworth, discussing Gross's case, described a patient who was sensitive to 3 per cent ammoniated mercury ointment but not to 1: 150 solution of mercurophen. Traub and Holmes2 reported on a patient with dermatitis and stomatitis due

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