At the meeting of the Vienese Dermatological Society in November 1927 one of us (M. O.)1 presented a patient with pemphigus serpiginosus who had been treated with acetarsone. This was a 58 year old woman who had an eruption of three and one-half months' duration. Acetarsone and exposure to ultraviolet radiation from a quartz mercury vapor lamp caused improvement with a tendency toward epithelization.
After this demonstration several cases of eruptions of the pemphigus group were published in which the disease was favorably influenced by acetarsone. Kromayer2 in 1929 reported 6 cases of pemphigus, including 2 in which it was severe, in which the eruption was healed. The drug was administered over a long period with intermissions. In 1 case 600 tablets were given. All the patients improved so that they were able to return to their former occupations. Relapses in the form of blisters and in 1
OPPENHEIM M, COHEN D. ACETARSONE IN THE TREATMENT OF PEMPHIGUS. Arch Derm Syphilol. 1943;47(1):40–42. doi:10.1001/archderm.1943.01500190043005
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