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January 1943


Arch Derm Syphilol. 1943;47(1):140-155. doi:10.1001/archderm.1943.01500190143020

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Lupus Erythematosus. Presented by Dr. Frederick G. Novy Jr., Oakland. Calif.  G. R., a 20 year old Italian laborer, was first seen in the University of California dermatologic clinic on April 21, 1942. Six months previously he had received 2 Gm. of sulfathiazole (2-[paraaminobenzenesulfonamido]-thiazole) daily for one week for a gonorrheal urethritis. This condition improved but recurred two weeks later. At the same time an eruption appeared on his face and then on his hands. The feet later became involved. He has lost 15 to 20 pounds (7 to 9 Kg.). He also complains of weakness and general malaise. His oral temperature has been as high as 38 C. (100.4 F.). Pain has been present between the shoulders and in the elbows.A general physical examination revealed evidence of illness and malaise. There were signs of pleural thickening at the base of the left lung. A rough systolic murmur could

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