Extensive alopecia is not a common clinical manifestation of keratosis follicularis. Most of the clinical reports and textbook descriptions, including Darier's own,1 mention involvement of the scalp as being similar to the crusting forms of seborrhea, sometimes with scaly papules but with no tendency to loss of hair. A patient with extensive lesions of the scalp associated with almost total alopecia and obliteration of most of the finger and toe nails, in addition to characteristic lesions of the skin, has been under my observation for over three years. Since this combination of abnormalities appears to be rare in keratosis follicularis, it is felt that the following report should be added to the literature.
REPORT OF CASE
F. C., a white woman aged 29, single, was first seen in January 1939. Since childhood she had had a generalized thickening and spiny roughness of the skin with such severe involvement
WELTON DG. KERATOSIS FOLLICULARIS WITH UNUSUAL INVOLVEMENT OF THE SCALP: REPORT OF A CASE. Arch Derm Syphilol. 1943;47(3):398–404. doi:10.1001/archderm.1943.01500210100006
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