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To the Editor:—
The incidence of sensitization to sulfonamide compounds is great enough to warrant limitation of their use to treatment of diseases for which they are indispensable. Since the topical exhibition of these drugs readily leads to sensitization in persons who are susceptible, dermatologists can do much to lessen unnecessary exposure to them.This is a plea for dermatologists not to cease experimenting with these drugs to seek out their value and place in their field of medicine but to refrain from using them for diseases that are common and for which effective therapy has long been available. I have in mind impetigo and pyoderma. By now, pharmaceutic manufacturers are recommending to members of the medical profession generally these drugs in ointment form for use against the aforementioned diseases. Would it be fair to deprive a patient of sulfonamide compounds for the treatment of pneumonia because previous use of
Sharlit H. SENSITIZATION TO SULFONAMIDE COMPOUNDS. Arch Derm Syphilol. 1943;47(4):585. doi:10.1001/archderm.1943.01500220123012
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