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Article
May 1943

VITAMIN B6 (PYRIDOXINE) IN DERMATOLOGY

Author Affiliations

PHILADELPHIA; MEDICAL CORPS, UNITED STATES ARMY; PHILADELPHIA

Arch Derm Syphilol. 1943;47(5):651-653. doi:10.1001/archderm.1943.01500230041007
Abstract

There are still many questions about vitamins that remain unanswered, although thousands of research workers and clinicians are giving considerable attention to their study. The medical literature is literally swamped with publications on vitamins, and it is with hesitation and mental reservations that an additional article is added, even after a two year study.

Little is known concerning the exact role of vitamin B6 (pyridoxine), which is only a small branch on the ever growing vitamin B complex tree, but the isolation of vitamin B6 was announced only in 1938 by Keresztesy and Stevens.1 Physiologic activity in acrodynia of the rat was first described by Antopol and Unna.2 Of considerable significance were the studies of Sullivan and Nicholls,3 who made the following observations: "In rats fed a basal vitamin B free diet supplemented with thiamin, riboflavin, nicotinic acid and filtrate factor, but completely devoid of

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