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Article
July 1943

ANGIOID STREAKS AND PSEUDOXANTHOMA ELASTICUM

Arch Derm Syphilol. 1943;48(1):75-82. doi:10.1001/archderm.1943.01510010079013
Abstract

Angioid streaks of the fundus and pseudoxanthoma elasticum of the skin are rare diseases of apparently unrelated organs which only recently have been considered as related conditions, and possibly as manifestations of a single systemic disease. The first condition was described first by Doyne1 (1889) and independently by Plange2 (1892) and was given the name "angioid streaks" by Knapp (1892).3

Balzar in 1884 (Ormsby4) first described a rare disease of the skin which Darier later (1896) called pseudoxanthoma elasticum (Throne and Goodman5). As early as 1903 Hallopeau and Laffitte6 described the association of pseudoxanthoma elasticum with angioid streaks, but it was not until the work of Grönblad7 (1929 and 1932) that the two diseases were generally associated and an attempt was made to correlate the etiologic factors in the two conditions.

ANGIOID STREAKS

Appearance.—On ophthalmoscopic examination angioid streaks appear as

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