Wagner,1 of Leipzig, in 1866 described the first reported example of colloid pseudomilium and called it "the colloid-milium of the skin." His patient was a healthy 54 year old woman with lesions across the forehead and on the upper portions of the cheeks and the bridge of the nose. The skin in these regions was thickened, hyperpigmented, furrowed and covered with numerous closely set millet grain-sized, round and oval, discrete papules. These looked, he said, exactly like vesicles, but differed from them in being distinctly solid (auffallend derb), so that it was impossible to rupture them with either finger tip or finger nail; moreover, when pricked with a needle they yielded no fluid except a drop of blood. By firm lateral pressure with a finger nail he was able to evacuate from the lesions little round or sausage-shaped masses of transparent whitish or pale yellowish material "like firm colloid."