We wish to report our observations in regard to histologic changes in psoriasis based on studies of 1 or more specimens removed for biopsy in more than 225 cases of psoriasis, the results of the histologic studies being correlated with the clinical findings and the course of the disease. The histogenesis of the disease is considered from the earliest lesion to lesions undergoing involution as the result of treatment; the lesions of various aberrant forms of psoriasis are also considered. We shall compare our observations with various older and newer concepts regarding the histogenesis of psoriasis as given in the literature. Space, however, permits reference only to some of the more important articles in the literature, which have been reviewed in the thesis by one of us (J. W. B.).
Specimens for biopsy were taken from various types of lesions in all stages of development and involution,
BURKS JW, MONTGOMERY H. HISTOPATHOLOGIC STUDY OF PSORIASIS. Arch Derm Syphilol. 1943;48(5):479–493. doi:10.1001/archderm.1943.01510050003001
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