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The occurrence of vitiligo in 3 members of one family is of sufficient rarity and interest to warrant reporting. Heredity as a factor in the following cases can apparently be ruled out, as careful examination of the father and mother failed to reveal any presence of the disease in them. There is also no history of vitiligo affecting the grandparents, paternal and maternal, or relatives of more distant kinship, such as uncles and aunts.
REPORT OF CASES
Case 1.—E. H., a white girl aged 18, first presented signs of vitiligo at the age of 8 years, with the appearance of typical milk-white lesions on both cheeks, the forehead and the chin. From these areas the disease steadily progressed to the V of the neck and then involved anterior surfaces of both forearms and the dorsa of both hands. The patient stated the belief that there is a slow but steady