Recently the subject of juxta-articular nodes as a manifestation of syphilis has aroused considerable interest in North America. However, of almost 200 cases reported from nontropical regions, only about 30 have been observed on this continent. According to Hudson,1 between 1 and 2 per cent of the population between the ages of 30 and 50 in the tropics is affected. The scarcity of reported cases in nontropical regions is, we believe, due in part to incorrect clinical diagnosis, and pertinent reasons will be mentioned later.
The purpose of this paper is to report a typical case and to review briefly the historical aspects of and the American literature on this subject.
Juxta-articular nodes may be defined as painless, slowly growing subcutaneous fibrous nodules, often symmetric in their distribution and if untreated of long duration. They are situated in the vicinity of a joint, especially of the extremities, and are
KALZ F, NEWTON BL. SYPHILITIC JUXTA-ARTICULAR NODULES. Arch Derm Syphilol. 1943;48(6):626–634. doi:10.1001/archderm.1943.01510060050008