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Article
April 1944

SUCCESSFUL INOCULATIONS OF ANIMALS WITH TRICHOPHYTON PURPUREUM: OBSERVATIONS ON THE COURSE OF THE DISEASE AND IMMUNOLOGIC AND HISTOLOGIC FEATURES

Arch Derm Syphilol. 1944;49(4):242-248. doi:10.1001/archderm.1944.01510100018005
Abstract

Since the report of Lewis, Montgomery and Hopper1 delineated the disease syndrome of chronic dermatophytosis, the clinical features of infection with Trichophyton purpureum have been fully recognized and wide attention has been paid to this type of dermatomycosis. Fungi can be found readily in scrapings from the affected skin and nail tissues either by the direct mount or by culture. Fungi can often be demonstrated at the sites of lesions which appear clinically cured. The latter fact may account for the frequent neglect of the disease by patients and for its recurrence. The common sites of involvement are the nail plates and regions with especially thick horny layers, e. g. the palms and soles. In relatively few instances the glabrous skin is affected. Therefore investigators have been inclined to consider the organism as infecting only the skin and nails and not the hair.

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