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Article
April 1944

ACRODERMATITIS CONTINUA (HALLOPEAU): EFFECT OF TREATMENT WITH SULFAPYRIDINE

Author Affiliations

BOSTON

From the Dermatologic Department of the Massachusetts General Hospital, C. Guy Lane, M.D., Chief.

Arch Derm Syphilol. 1944;49(4):273-277. doi:10.1001/archderm.1944.01510100049015
Abstract

The purpose of this communication is to report a case of acrodermatitis continua (Hallopeau) of eleven years' duration in which sulfapyridine caused complete disappearance of the lesions and prevented the appearance of new lesions as long as it was given in adequate amounts. Reports of 2 cases of acrodermatitis continua in which treatment with sulfonamide compounds had been successful were found in abstracts of transactions of meetings of dermatologic societies. It appears, therefore, as if at last a successful treatment has been found for a disease which so far has resisted all therapeutic efforts. Although the cause of acrodermatitis continua is still unknown, certain conclusions regarding it may be drawn from the fact that sulfapyridine controls the symptoms.

REVIEW OF THE LITERATURE

Mahn,1 in 1938, was the first to treat acrodermatitis continua with a sulfonamide compound. In the report of a case he stated

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